Sunday, April 17, 2011

New high impact articles - Novel family of stress-protective proteins and pexophagy

A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigates
Sak Hoi et al
MBoC in Press, published April 13, 2011
Authors identified two novel proteins DprA and DprB which are important for peroxisome functioning. Both of these proteins when fused to eGFP localize to peroxisomes and cytosol. Dpr mutants exhibit  altered catalase levels and impaired peroxisomal beta-oxidation.

Zutphen et al
Autophagy (Impact Factor - 6.829)
Volume 7, Issue 8   August 2011
Authors identified the massive peroxisome degradation process resembling both micro and macro-pexophagy using Pex3 fused with temperature sensitive degron sequence at N-terminus.

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